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- Shannen Doherty
- Desmond Doig
- Robert Doisneau
- Jay P. Dolan
- Thomas Dolby
- Bob Dole
- Elizabeth Dole
- Robert J. Dole
- Marcus Dolengo
- Eric Dolphy
- Pete Domenici
- Placido Domingo
- Fats Domino
- Mike Donahue
- Phil Donahue
- David Herbert Donald
- Sam Donaldson
- Richard Donat
- Gaetano Donizetti
- J. P. Donleavy
- John Donne
- James A. Donovan
- Maria Donovan
- Raymond J. Donovan
- Terence Donovan
- James Doohan
- Stephen Dooley, Jr.
- Dr. Thomas Dooley
- Jimmy Doolittle
- Matt Doran
- Mamie Van Doren
- Mark Van Doren
- Lou Dorfsman
- Byron Dorgan
- Larry Dorman

- Michael Dorris
- Tony Dorsett
- George A. Dorsey
- George Dorsey
- Tommy Dorsey
- Larry Dossey
- Fyodor Dostoevsky
- Fyodor Dostoyevsky
- Dave Del Dotto
- N. W. Dougherty
- Alec Douglas-Home
- Alfred Douglas
- Ann Douglas
- David Douglas
- Denzil Douglas
- Donald Douglas
- Donald Wills Douglas
- Frederick Douglas
- George Douglas
- George Norman Douglas
- Helen Gahagan Douglas
- I. D. Douglas
- Jack Douglas
- James Douglas
- James H. Douglas
- Kirk Douglas
- Lloyd C. Douglas
- Lord Alfred Douglas
- Mack R. Douglas
- Melvyn Douglas
- Michael Douglas
- Norman Douglas
- Stephen Douglas
- T. C. Douglas
- Tommy Douglas