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- Gordon England
- Jim England
- Paul Engle
- Jon English
- Ted W. Engstrom
- Ennius
- Quintus Ennius
- Brian Eno
- Roger Enrico
- John Ensign
- Enya
- Hans Magnus Enzensberger
- Michael Enzi
- Delia Ephron
- Nora Ephron
- Epicharmus
- Epictetus
- Epicurus
- Jacob Epstein
- Joseph Epstein
- Desiderius Erasmus
- Eratosthenes
- Paul Erdman
- Martin Erdmann
- Paul Erdos
- Louise Erdrich
- Ludwig Erhard
- Werner Erhard
- John Eric Ericksen
- Lou Erickson
- Roger Erickson
- John Ericsson
- Stephanie Ericsson
- Erik Erikson
- Erik H. Erikson

- John Erksine
- Ernesto
- Max Ernst
- John Erskine
- Thomas Erskine
- Susan Ertz
- Sam Ervin
- Julius Erving
- Ira Erwin
- Elliott Erwitt
- Evan Esar
- Marie Ebner Von Eschenbach
- M. C. Escher
- Lord Esher
- Levi Eshkol
- Richard Espy
- William Esrey
- Harmutt Esslinger
- Gloria Estefan
- Clarissa Pinkola Estes
- James Estes
- Simon Estes
- Emilio Estevez
- Henri Estienne
- Ignacio Estrada
- L. Estrange
- Bob Etheridge
- Melissa Etheridge
- Euclid
- Leonhard Euler
- Euripedes
- Euripides
- Max Euwe
- Anthony Euwer
- Linda Evangelista